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Antikörper

CD2AP Antibody

Produktgrößen
100ul
£359,00
OACD02315-100UL
1ml
£1016,00
OACD02315-1ML
Über dieses Produkt
SKU:
OACD02315
Zusätzliche Namen:
adapter protein CMS;cas ligand with multiple SH3 domains;Cas ligand with multiple Src homology 3 (SH3) domains;CD2-associated protein;CMS.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC; modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function; converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260).
Gendetails:
CD2 associated protein
Host:
Rabbit
Immunogen:
Range: Thr149 - Glu429
Isotyp:
IgG
Molekulargewicht:
71 kDa
Proteindetails:
CD2-associated protein
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody