CD14 Antibody
Produktgrößen
100ul
£355,00
OACD02294-100UL
1ml
£998,00
OACD02294-1ML
Über dieses Produkt
- SKU:
- OACD02294
- Zusätzliche Namen:
- Myeloid cell-specific leucine-rich glycoprotein.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Coreceptor for bacterial lipopolysaccharide. In concert with LBP; binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex; thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88; TIRAP and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides; these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
- Gendetails:
- Cluster Of Differentiation 14
- Host:
- Rabbit
- Immunogen:
- Range: Thr21 - Ala373
- Isotyp:
- IgG
- Molekulargewicht:
- 40 kDa
- Proteindetails:
- Monocyte differentiation antigen CD14
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php