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Antikörper

CASR Antibody

Produktgrößen
100ul
£344,00
OACD02228-100UL
1ml
£955,00
OACD02228-1ML
Über dieses Produkt
SKU:
OACD02228
Zusätzliche Namen:
C;CaR;cation sensing receptor;extracellular calcium-sensing receptor;G protein-coupled receptor; family C; group 2; member A;Gpr;Gprc2a;parathyroid cell calcium-sensing receptor;PCaR1.
Klonalität:
Polyclonal
Konzentration:
0.31 mg/ml
Weitere Details:
G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (PubMed:7493018). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids; such as Trp or Phe; act concertedly with divalent cations; such as calcium or magnesium; to achieve full receptor activation (By similarity).
Gendetails:
calcium-sensing receptor
Host:
Rabbit
Immunogen:
Range: Lys863 - Ser1079
Isotyp:
IgG
Molekulargewicht:
112 kDa
Proteindetails:
Extracellular calcium-sensing receptor
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody