APC Antibody
Produktgrößen
100ul
£355,00
OACD01699-100UL
1ml
£1005,00
OACD01699-1ML
Über dieses Produkt
- SKU:
- OACD01699
- Zusätzliche Namen:
- adenomatosis polyposis coli;adenomatous polyposis coli protein;APC; WNT signaling pathway regulator;RATAPC;WNT signaling pathway regulator.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.99 mg/ml
- Weitere Details:
- Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization (By similarity).
- Gendetails:
- APC regulator of WNT signaling pathway
- Host:
- Rabbit
- Immunogen:
- Range: Ala2634 - Val2842
- Isotyp:
- IgG
- Molekulargewicht:
- 311 kDa
- Proteindetails:
- Adenomatous polyposis coli protein
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php