ALOX12 Antibody
Produktgrößen
100ul
£322,00
OACD01568-100UL
1ml
£890,00
OACD01568-1ML
Über dieses Produkt
- SKU:
- OACD01568
- Zusätzliche Namen:
- 12-LOX;12S-lipoxygenase;12S-LOX;arachidonate (12S)-lipoxygenase;arachidonate (15S)-lipoxygenase;Arachidonate 12-lipoxygenase; 12S-type;arachidonate 15-lipoxygenase;15S-type;linoleate 13S-lipoxygenase;lipoxin synthase 12-LO;LOG12;platelet 12-LOX;platelet-type 12-lipoxygenase;platelet-type lipoxygenase 12;polyunsaturated fatty acid lipoxygenase ALOX12.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process; promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
- Gendetails:
- arachidonate 12-lipoxygenase; 12S type
- Host:
- Rabbit
- Immunogen:
- Range: Phe352 - Cys656
- Isotyp:
- IgG
- Molekulargewicht:
- 76 kDa
- Proteindetails:
- Arachidonate 12-lipoxygenase; 12S-type
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php