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Antikörper

ABCA4 Antibody

Produktgrößen
100ul
£333,00
OACD01318-100UL
1ml
£933,00
OACD01318-1ML
Über dieses Produkt
SKU:
OACD01318
Zusätzliche Namen:
ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter; retinal-specific;ATP-binding cassette; sub-family A (ABC1); member 4;ATP-binding transporter; retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
In the visual cycle; acts as an inward-directed retinoid flipase; retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface; ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse; removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
Gendetails:
ATP binding cassette subfamily A member 4
Host:
Rabbit
Immunogen:
Recombinant ABCA4 (Gly1398~Asn1727) expressed in E.coli
Isotyp:
IgG
Molekulargewicht:
256 kDa
Proteindetails:
Retinal-specific ATP-binding cassette transporter
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody