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Antikörper

A2ML1 Antibody

Produktgrößen
100ul
£311,00
OACD01297-100UL
1ml
£853,00
OACD01297-1ML
Über dieses Produkt
SKU:
OACD01297
Zusätzliche Namen:
alpha-2-macroglobulin-like protein 1;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9;C3 and PZP-like; alpha-2-macroglobulin domain containing 9;CPAMD9;OMS;p170.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch; called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region; a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin; papain; thermolysin; subtilisin A and; to a lesser extent; elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.
Gendetails:
alpha-2-macroglobulin like 1
Host:
Rabbit
Immunogen:
Range: Gln1119 - Thr1348
Isotyp:
IgG
Molekulargewicht:
106 kDa
Proteindetails:
Alpha-2-macroglobulin-like protein 1
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody