ACD Antibody
Produktgrößen
100ul
£355,00
OACD01237-100UL
1ml
£1005,00
OACD01237-1ML
Über dieses Produkt
- SKU:
- OACD01237
- Zusätzliche Namen:
- adrenocortical dysplasia homolog;adrenocortical dysplasia protein homolog.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity; telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
- Gendetails:
- ACD; shelterin complex subunit and telomerase recruitment factor
- Host:
- Rabbit
- Immunogen:
- Range: Asn147 - Glu342
- Isotyp:
- IgG
- Molekulargewicht:
- 46 kDa
- Proteindetails:
- Adrenocortical dysplasia protein homolog
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php