EXO1 Antibody
Produktgrößen
100ul
£333,00
OACD00904-100UL
1ml
£933,00
OACD00904-1ML
Über dieses Produkt
- SKU:
- OACD00904
- Zusätzliche Namen:
- exonuclease 1;Exonuclease I;HEX1;hExoI;rad2 nuclease family member; homolog of S. cerevisiae exonuclease 1.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
- Gendetails:
- exonuclease 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Ile250
- Isotyp:
- IgG
- Molekulargewicht:
- 89 kDa
- Proteindetails:
- Exonuclease 1
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php