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Antikörper

DKC1 Antibody

Produktgrößen
100ul
£333,00
OACD00892-100UL
1ml
£933,00
OACD00892-1ML
Über dieses Produkt
SKU:
OACD00892
Zusätzliche Namen:
CBF5;CBF5 homolog;DKC;DKCX;dyskeratosis congenita 1; dyskerin;Dyskerin;H/ACA ribonucleoprotein complex subunit 4;H/ACA ribonucleoprotein complex subunit DKC1;NAP57;NOLA4;nopp140-associated protein of 57 kDa;nucleolar protein family A member 4;nucleolar protein NAP57;snoRNP protein DKC1;XAP101.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Isoform 1: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex; which catalyzes pseudouridylation of rRNA (PubMed:25219674). This involves the isomerization of uridine such that the ribose is subsequently attached to C5; instead of the normal N1 (PubMed:25219674). Each rRNA can contain up to 100 pseudouridine ('psi') residues; which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance (PubMed:19179534; PubMed:25219674). Also required for correct processing or intranuclear trafficking of TERC; the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (PubMed:19179534).
Gendetails:
dyskerin pseudouridine synthase 1
Host:
Rabbit
Immunogen:
Range: Arg298 - Leu465
Isotyp:
IgG
Molekulargewicht:
48 kDa
Proteindetails:
H/ACA ribonucleoprotein complex subunit DKC1
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody