DKK1 Antibody
Produktgrößen
100ul
£326,00
OACD00245-100UL
200ul
£420,00
OACD00245-200UL
1ml
£901,00
OACD00245-1ML
Über dieses Produkt
- SKU:
- OACD00245
- Zusätzliche Namen:
- dickkopf 1 homolog;dickkopf-1 like;dickkopf-like protein 1;dickkopf-related protein 1;DKK-1;SK.
- translate.label.attr.clone:
- 17#
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner; and has anti-apoptotic activity (By similarity).
- Gendetails:
- dickkopf WNT signaling pathway inhibitor 1
- Host:
- Mouse
- Immunogen:
- <a href='//www.avivasysbio.com/dkk1-recombinant-protein-opcd02745.html' target='_blank'>DKK1 Recombinant Protein (OPCD02745)</a>
- Isotyp:
- IgG2b Kappa
- Proteindetails:
- Dickkopf-related protein 1
- Aufreinigung:
- Protein A/G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php