CRTC1 Antibody
Produktgrößen
50ug
£305,00
OACA10593-50UG
100ug
£463,00
OACA10593-100UG
Über dieses Produkt
- SKU:
- OACA10593
- Zusätzliche Namen:
- CREB-regulated transcription coactivator 1;Mam-2;MAML2;Mastermind-like protein 2;MECT1;mucoepidermoid carcinoma translocated protein 1;TORC1;TORC-1;transducer of regulated cAMP response element-binding protein (CREB) 1;Transducer of regulated cAMP response element-binding protein 1;WAMTP1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator; in the SIK/TORC signaling pathway; being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene; StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus; involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1; regulates the light-induced entrainment of the circadian clock. In response to light stimulus; coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
- Gendetails:
- CREB regulated transcription coactivator 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CREB-regulated transcription coactivator 1 protein (1-248AA)
- Isotyp:
- IgG
- Proteindetails:
- CREB-regulated transcription coactivator 1
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php