BECN1 Antibody
Produktgrößen
50ug
£305,00
OACA10550-50UG
100ug
£463,00
OACA10550-100UG
Über dieses Produkt
- SKU:
- OACA10550
- Zusätzliche Namen:
- ATG6;ATG6 autophagy related 6 homolog;beclin 1 (coiled-coil; moesin-like BCL2-interacting protein);beclin 1; autophagy related;beclin1;beclin-1;coiled-coil myosin-like BCL2-interacting protein;Protein GT197;testis secretory sperm-binding protein Li 215e;VPS30.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Plays a central role in autophagy (PubMed:23184933; PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis; probably in the context of PI3KC3-C2 (PubMed:20643123; PubMed:20208530; PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
- Gendetails:
- beclin 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Beclin-1 protein (1-100AA)
- Isotyp:
- IgG
- Proteindetails:
- Beclin-1
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php