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Antikörper

FCHO2 Antibody

Produktgrößen
50ug
£305,00
OACA10212-50UG
100ug
£463,00
OACA10212-100UG
Über dieses Produkt
SKU:
OACA10212
Zusätzliche Namen:
F-BAR domain only protein 2;FCH domain only 2;FCH domain only protein 2.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
Varies by lot. See vial for exact concentration.
Weitere Details:
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4;5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor; it also functions in the AP-2-independent endocytosis of the LDL receptor.
Gendetails:
FCH and mu domain containing endocytic adaptor 2
Host:
Rabbit
Immunogen:
Recombinant Human F-BAR domain only protein 2 protein (100-203AA)
Isotyp:
IgG
Proteindetails:
F-BAR domain only protein 2
Reinheit:
>95%
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody