DISC1 Antibody
Produktgrößen
50ug
£305,00
OACA10117-50UG
100ug
£463,00
OACA10117-100UG
Über dieses Produkt
- SKU:
- OACA10117
- Zusätzliche Namen:
- C1orf136;disrupted in schizophrenia 1 protein;SCZD9.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis; including neuron positioning; dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role; together with PCNT; in the microtubule network formation.
- Gendetails:
- DISC1 scaffold protein
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Disrupted in schizophrenia 1 protein (99-325AA)
- Isotyp:
- IgG
- Proteindetails:
- Disrupted in schizophrenia 1 protein
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php