DNAJB6 Antibody
Produktgrößen
50ug
£305,00
OACA10046-50UG
100ug
£463,00
OACA10046-100UG
Über dieses Produkt
- SKU:
- OACA10046
- Zusätzliche Namen:
- DJ4;DnaJ;DnaJ (Hsp40) homolog; subfamily B; member 6;dnaJ homolog subfamily B member 6;DnaJ-like 2 protein;heat shock protein J2;HHDJ1;HSJ2;HSJ-2;LGMD1D;LGMD1E;LGMDD1;MRJ;MSJ-1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing; aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
- Gendetails:
- DnaJ heat shock protein family (Hsp40) member B6
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)
- Isotyp:
- IgG
- Proteindetails:
- DnaJ homolog subfamily B member 6
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php