CCNC Antibody
Produktgrößen
50ug
£305,00
OACA09985-50UG
100ug
£463,00
OACA09985-100UG
Über dieses Produkt
- SKU:
- OACA09985
- Zusätzliche Namen:
- CycC;cyclin-C;hSRB11;SRB11;SRB11 homolog.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the Mediator complex; a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II); which may inhibit the formation of a transcription initiation complex.
- Gendetails:
- cyclin C
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cyclin-C protein (240-283AA)
- Isotyp:
- IgG
- Proteindetails:
- Cyclin-C
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php