DOCK7 Antibody
Produktgrößen
50ug
£305,00
OACA09922-50UG
100ug
£463,00
OACA09922-100UG
Über dieses Produkt
- SKU:
- OACA09922
- Zusätzliche Namen:
- dedicator of cytokinesis protein 7;DEE23;EIEE23;ZIR2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Functions as a guanine nucleotide exchange factor (GEF); which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
- Gendetails:
- dedicator of cytokinesis 7
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
- Isotyp:
- IgG
- Proteindetails:
- Dedicator of cytokinesis protein 7
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php