CHTOP Antibody
Produktgrößen
50ug
£305,00
OACA09732-50UG
100ug
£463,00
OACA09732-100UG
Über dieses Produkt
- SKU:
- OACA09732
- Zusätzliche Namen:
- C10orf77;C1orf77;chromatin target of PRMT1 protein;FL-SRAG;FOP;friend of PRMT1 protein;pp7704;Small arginine- and glycine-rich protein;small protein rich in arginine and glycine;SRAG;SRAG-3;SRAG-5.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Plays an important role in the ligand-dependent activation of estrogen receptor target genes (PubMed:19858291). May play a role in the silencing of fetal globin genes (PubMed:20688955). Recruits the 5FMC complex to ZNF148; leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Plays an important role in the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1; PRMT5; MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC is recruited to selective sites on the chromosome; where it methylates H4R3 and activates the transcription of genes involved in glioblastomagenesis (PubMed:25284789).
- Gendetails:
- chromatin target of PRMT1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Chromatin target of PRMT1 protein (179-248AA)
- Isotyp:
- IgG
- Proteindetails:
- Chromatin target of PRMT1 protein
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php