DHX33 Antibody
Produktgrößen
50ug
£305,00
OACA09715-50UG
100ug
£463,00
OACA09715-100UG
Über dieses Produkt
- SKU:
- OACA09715
- Zusätzliche Namen:
- ATP-dependent RNA helicase DHX33;DDX33;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 33;DEAH (Asp-Glu-Ala-His) box polypeptide 33;DEAH box protein 33;putative ATP-dependent RNA helicase DHX33.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Implicated in nucleolar organization; ribosome biogenesis; protein synthesis and cytoplasmic dsRNA sensing (By similarity) (PubMed:21930779; PubMed:23871209; PubMed:26100019). Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment (PubMed:21930779). In the cytoplasm; promotes elongation-competent 80S ribosome assembly at the late stage of mRNA translation initiation (PubMed:26100019). Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells (PubMed:23871209). Required for NLRP3 activation induced by viral dsRNA and bacterial RNA (PubMed:23871209). In dendritic cells; required for induction of type I interferon production induced by cytoplasmic dsRNA via the activation of MAPK and NF-kappa-B signaling pathways (By similarity).
- Gendetails:
- DEAH-box helicase 33
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ATP-dependent RNA helicase DHX33 protein (116-357AA)
- Isotyp:
- IgG
- Proteindetails:
- ATP-dependent RNA helicase DHX33
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php