C7ORF49 Antibody
Produktgrößen
50ug
£305,00
OACA09712-50UG
100ug
£463,00
OACA09712-100UG
Über dieses Produkt
- SKU:
- OACA09712
- Zusätzliche Namen:
- C7orf49;cell cycle regulator of non-homologous end joining;modulator of retrovirus infection homolog;MRI;MRI-2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Isoform 1: Cell-cycle-specific inhibitor of classical non-homologous end joining (NHEJ) of DNA double-strand break (DSB) repair during the S and G2 phases (PubMed:28959974). Acts as a regulator of DNA repair pathway choice by specifically inhibiting classical NHEJ during the S and G2 phases; thereby promoting error-free repair by homologous recombination during cell cycle phases when sister chromatids are present (PubMed:28959974). Preferentially protects single-stranded overhangs at break sites by inhibiting classical NHEJ; thereby creating a local environment that favors homologous recombination (PubMed:28959974). Acts via interaction with XRCC5/Ku80 and XRCC6/Ku70; interaction restricted during the S and G2 phases only (PubMed:28959974). Molecular mechanisms governing classical NHEJ inhibition via interaction with XRCC5/Ku80 and XRCC6/Ku70 are unknown (PubMed:28959974). May act as a regulator of proteasome (By similarity).
- Gendetails:
- cell cycle regulator of NHEJ
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cell cycle regulator of non-homologous end joining protein (1-157AA)
- Isotyp:
- IgG
- Proteindetails:
- Cell cycle regulator of non-homologous end joining
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php