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Antikörper

A2M Antibody

Produktgrößen
50ug
£305,00
OACA09518-50UG
100ug
£463,00
OACA09518-100UG
Über dieses Produkt
SKU:
OACA09518
Zusätzliche Namen:
A2MD;alpha-2-M;alpha-2-macroglobulin;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5;CPAMD5;FWP007;S863-7.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch; called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region; a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region; a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Gendetails:
alpha-2-macroglobulin
Host:
Rabbit
Immunogen:
Recombinant Human Alpha-2-macroglobulin protein (1216-1467AA)
Isotyp:
IgG
Proteindetails:
Alpha-2-macroglobulin
Reinheit:
>95%
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody