FAM65B Antibody
Produktgrößen
50ug
£305,00
OACA09375-50UG
100ug
£463,00
OACA09375-100UG
Über dieses Produkt
- SKU:
- OACA09375
- Zusätzliche Namen:
- C6orf32;DFNB104;DIFF40;DIFF48;FAM65B;family with sequence similarity 65 member B;myogenesis-related and NCAM-associated protein homolog;MYONAP;PL48;protein FAM65B;rho family-interacting cell polarization regulator 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation; lymphocyte T proliferation and neutrophil polarization (PubMed:17150207; PubMed:24687993; PubMed:23241886; PubMed:24958875; PubMed:25588844; PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses; such as cell adhesion; polarization and migration (PubMed:23241886). Involved also in the regulation of neutrophil polarization; chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maintaining the structural organization of the basal domain of stereocilia (By similarity). Involved in mechanosensory hair cell function (By similarity). Required for normal hearing (PubMed:24958875).
- Gendetails:
- RHO family interacting cell polarization regulator 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Rho family-interacting cell polarization regulator 2 protein (1-250AA)
- Isotyp:
- IgG
- Proteindetails:
- Rho family-interacting cell polarization regulator 2
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php