E2F1 Antibody
Produktgrößen
50ug
£305,00
OACA09364-50UG
100ug
£463,00
OACA09364-100UG
Über dieses Produkt
- SKU:
- OACA09364
- Zusätzliche Namen:
- E2F-1;PBR3;PRB-binding protein E2F-1;RBAP1;RBAP-1;RBBP3;RBBP-3;RBP3;retinoblastoma-associated protein 1;retinoblastoma-binding protein 3;transcription factor E2F1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site; 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Positively regulates transcription of RRP1B (PubMed:20040599).
- Gendetails:
- E2F transcription factor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Transcription factor E2F1 protein (133-362AA)
- Isotyp:
- IgG
- Proteindetails:
- Transcription factor E2F1
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php