DACH1 Antibody
Produktgrößen
50ug
£305,00
OACA09359-50UG
100ug
£463,00
OACA09359-100UG
Über dieses Produkt
- SKU:
- OACA09359
- Zusätzliche Namen:
- dac homolog;DACH;dachshund homolog 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1; SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors; including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
- Gendetails:
- dachshund family transcription factor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dachshund homolog 1 protein (166-369AA)
- Isotyp:
- IgG
- Proteindetails:
- Dachshund homolog 1
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php