CNOT1 Antibody
Produktgrößen
50ug
£305,00
OACA09356-50UG
100ug
£463,00
OACA09356-100UG
Über dieses Produkt
- SKU:
- OACA09356
- Zusätzliche Namen:
- AD-005;adrenal gland protein AD-005;CCR4-associated factor 1;CCR4-NOT transcription complex subunit 1;CDC39;HPE12;negative regulator of transcription subunit 1 homolog;NOT1;NOT1 (negative regulator of transcription 1; yeast) homolog;NOT1H;VIBOS.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation; miRNA-mediated repression; translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A; TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem (ES) cell identity.
- Gendetails:
- CCR4-NOT transcription complex subunit 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CCR4-NOT transcription complex subunit 1 protein (604-867AA)
- Isotyp:
- IgG
- Proteindetails:
- CCR4-NOT transcription complex subunit 1
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php