AHR Antibody
Produktgrößen
50ug
£305,00
OACA09332-50UG
100ug
£463,00
OACA09332-100UG
Über dieses Produkt
- SKU:
- OACA09332
- Zusätzliche Namen:
- ah receptor;AH-receptor;aromatic hydrocarbon receptor;aryl hydrocarbon receptor;bHLHe76;class E basic helix-loop-helix protein 76;RP85.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820).
- Gendetails:
- aryl hydrocarbon receptor
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)
- Isotyp:
- IgG
- Proteindetails:
- Aryl hydrocarbon receptor
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php