CSPG4 Antibody
Produktgrößen
50ul
£316,00
OACA09170-50UL
100ul
£387,00
OACA09170-100UL
Über dieses Produkt
- SKU:
- OACA09170
- Zusätzliche Namen:
- chondroitin sulfate proteoglycan 4;chondroitin sulfate proteoglycan 4 (melanoma-associated);chondroitin sulfate proteoglycan NG2;CSPG4A;HMW-MAA;MCSP;MCSPG;melanoma chondroitin sulfate proteoglycan;melanoma-associated chondroitin sulfate proteoglycan;MEL-CSPG;MSK16;NG2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors; extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4; beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42; ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
- Gendetails:
- chondroitin sulfate proteoglycan 4
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Chondroitin sulfate proteoglycan 4 protein (1950-2210AA)
- Isotyp:
- IgG
- Proteindetails:
- Chondroitin sulfate proteoglycan 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php