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Antikörper

BLOC1S2 Antibody

Produktgrößen
50ul
£316,00
OACA08729-50UL
100ul
£387,00
OACA08729-100UL
Über dieses Produkt
SKU:
OACA08729
Zusätzliche Namen:
11 kDa centrosome associated protein;biogenesis of lysosome-related organelles complex 1 subunit 2;BLOC-1 subunit 2;BLOS2;BORCS2;CEAP;CEAP11;centrosomal 10 kDa protein;centrosome protein oncogene;Centrosome-associated protein.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Component of the BLOC-1 complex; a complex that is required for normal biogenesis of lysosome-related organelles (LRO); such as platelet dense granules and melanosomes (PubMed:15102850; PubMed:17182842). In concert with the AP-3 complex; the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex; in association with SNARE proteins; is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes; the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421).
Gendetails:
biogenesis of lysosomal organelles complex 1 subunit 2
Host:
Rabbit
Immunogen:
Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (44-142AA)
Isotyp:
IgG
Proteindetails:
Biogenesis of lysosome-related organelles complex 1 subunit 2
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody