ERLIN2 Antibody
Produktgrößen
50ul
£316,00
OACA08616-50UL
100ul
£387,00
OACA08616-100UL
Über dieses Produkt
- SKU:
- OACA08616
- Zusätzliche Namen:
- C8orf2;endoplasmic reticulum lipid raft-associated protein 2;epididymis secretory sperm binding protein;erlin-2;NET32;spastic paraplegia 18 (autosomal dominant);SPFH domain family; member 2;SPFH2;SPG18;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1;4;5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031; PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
- Gendetails:
- ER lipid raft associated 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Erlin-2 protein (212-339AA)
- Isotyp:
- IgG
- Proteindetails:
- Erlin-2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php