DOCK8 Antibody
Produktgrößen
50ul
£316,00
OACA08615-50UL
100ul
£387,00
OACA08615-100UL
Über dieses Produkt
- SKU:
- OACA08615
- Zusätzliche Namen:
- 1200017A24Rik;dedicator of cytokinesis protein 8;epididymis luminal protein 205;HEL-205;MRD2;ZIR8.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP (PubMed:28028151; PubMed:22461490). During immune responses; required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC (By similarity). Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane (PubMed:28028151). Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing center (MTOC); and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing (PubMed:25762780).
- Gendetails:
- dedicator of cytokinesis 8
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dedicator of cytokinesis protein 8 protein (1900-2099AA)
- Isotyp:
- IgG
- Proteindetails:
- Dedicator of cytokinesis protein 8
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php