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Antikörper

ARL6 Antibody

Produktgrößen
50ul
£316,00
OACA08540-50UL
100ul
£387,00
OACA08540-100UL
Über dieses Produkt
SKU:
OACA08540
Zusätzliche Namen:
ADP-ribosylation factor-like protein 6;Bardet-Biedl syndrome 3 protein;BBS3;RP55.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1; is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1; controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).
Gendetails:
ADP ribosylation factor like GTPase 6
Host:
Rabbit
Immunogen:
Recombinant Human ADP-ribosylation factor-like protein 6 protein (1-186AA)
Isotyp:
IgG
Proteindetails:
ADP-ribosylation factor-like protein 6
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody