DNAJB9 Antibody
Produktgrößen
50ul
£316,00
OACA08306-50UL
100ul
£387,00
OACA08306-100UL
Über dieses Produkt
- SKU:
- OACA08306
- Zusätzliche Namen:
- DnaJ (Hsp40) homolog; subfamily B; member 9;dnaJ homolog subfamily B member 9;endoplasmic reticulum DNA J domain-containing protein 4;endoplasmic reticulum DnaJ homolog 4;ERdj4;ER-resident protein ERdj4;MDG1;MDG-1;microvascular endothelial differentiation gene 1 protein;MST049;MSTP049.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (PubMed:18400946). In the unstressed endoplasmic reticulum; interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region; thereby inactivating ERN1/IRE1 (By similarity). Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production (By similarity).
- Gendetails:
- DnaJ heat shock protein family (Hsp40) member B9
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaJ homolog subfamily B member 9 protein (24-223AA)
- Isotyp:
- IgG
- Proteindetails:
- DnaJ homolog subfamily B member 9
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php