CALCOCO2 Antibody
Produktgrößen
50ul
£316,00
OACA08298-50UL
100ul
£387,00
OACA08298-100UL
Über dieses Produkt
- SKU:
- OACA08298
- Zusätzliche Namen:
- antigen nuclear dot 52 kDa protein;calcium-binding and coiled-coil domain-containing protein 2;NDP52;nuclear domain 10 protein 52;nuclear domain 10 protein NDP52;nuclear dot protein 52.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382; PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A; MAP1LC3B and/or GABARAPL2; whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382; PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).
- Gendetails:
- calcium binding and coiled-coil domain 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Calcium-binding and coiled-coil domain-containing protein 2 protein (137-446AA)
- Isotyp:
- IgG
- Proteindetails:
- Calcium-binding and coiled-coil domain-containing protein 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php