DPF1 Antibody
Produktgrößen
50ul
£316,00
OACA08255-50UL
100ul
£387,00
OACA08255-100UL
Über dieses Produkt
- SKU:
- OACA08255
- Zusätzliche Namen:
- BAF45b;BRG1-associated factor 45B;D4; zinc and double PHD fingers family 1;NEUD4;neuro-d4;neuro-d4 homolog;SMARCG1;zinc finger protein neuro-d4.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- May have an important role in developing neurons by participating in regulation of cell survival; possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons; npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A; are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- Gendetails:
- double PHD fingers 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)
- Isotyp:
- IgG
- Proteindetails:
- Zinc finger protein neuro-d4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php