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Antikörper

ELF4 Antibody

Produktgrößen
50ul
£316,00
OACA07841-50UL
100ul
£387,00
OACA07841-100UL
Über dieses Produkt
SKU:
OACA07841
Zusätzliche Namen:
E74-like factor 4;E74-like factor 4 (ets domain transcription factor);ELFR;ETS-related transcription factor Elf-4;MEF;myeloid Elf-1-like factor.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2; IL3; IL8; and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Gendetails:
E74 like ETS transcription factor 4
Host:
Rabbit
Immunogen:
Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)
Isotyp:
IgG
Proteindetails:
ETS-related transcription factor Elf-4
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody