EIF3H Antibody
Produktgrößen
50ul
£316,00
OACA07767-50UL
100ul
£387,00
OACA07767-100UL
Über dieses Produkt
- SKU:
- OACA07767
- Zusätzliche Namen:
- eIF3 p40 subunit;eIF3-gamma;eIF-3-gamma;eIF3-p40;EIF3S3;eukaryotic translation initiation factor 3 subunit 3;eukaryotic translation initiation factor 3 subunit H;eukaryotic translation initiation factor 3; subunit 2 (beta; 36kD);eukaryotic translation initiation factor 3; subunit 3 (gamma; 40kD);eukaryotic translation initiation factor 3; subunit 3 gamma; 40kDa.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773; PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Gendetails:
- eukaryotic translation initiation factor 3 subunit H
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Eukaryotic translation initiation factor 3 subunit H protein (80-340AA)
- Isotyp:
- IgG
- Proteindetails:
- Eukaryotic translation initiation factor 3 subunit H
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php