COLEC11 Antibody
Produktgrößen
50ul
£316,00
OACA07657-50UL
100ul
£387,00
OACA07657-100UL
Über dieses Produkt
- SKU:
- OACA07657
- Zusätzliche Namen:
- 3MC2;CL-11;CLK1;CL-K1-I;CL-K1-II;CL-K1-IIa;CL-K1-IIb;Collectin K1;collectin kidney protein 1;collectin sub-family member 11;collectin-11.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Lectin that plays a role in innate immunity; apoptosis and embryogenesis (PubMed:23954398; PubMed:25912189; PubMed:21258343). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1;2-linked mannose epitope (PubMed:25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed:25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed:17179669; PubMed:25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed:20956340; PubMed:25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally; plays a role in development; probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed:21258343; PubMed:28301481).
- Gendetails:
- collectin subfamily member 11
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Collectin-11 protein (26-271AA)
- Isotyp:
- IgG
- Proteindetails:
- Collectin-11
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php