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Antikörper

AKAP10 Antibody

Produktgrößen
50ul
£316,00
OACA07492-50UL
100ul
£387,00
OACA07492-100UL
Über dieses Produkt
SKU:
OACA07492
Zusätzliche Namen:
A kinase (PRKA) anchor protein 10;AKAP-10;A-kinase anchor protein 10; mitochondrial;D-AKAP2;D-AKAP-2;dual specificity A kinase-anchoring protein 2;mitochondrial A kinase PPKA anchor protein 10;PRKA10;protein kinase A anchoring protein 10;Protein kinase A-anchoring protein 10.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood; one idea is that BAD; a proapoptotic member; is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction; by acting as an adapter for assembling multiprotein complexes. With its RGS domain; it could lead to the interaction to G-alpha proteins; providing a link between the signaling machinery and the downstream kinase (By similarity).
Gendetails:
A-kinase anchoring protein 10
Host:
Rabbit
Immunogen:
Recombinant Human A-kinase anchor protein 10; mitochondrial protein (413-662AA)
Isotyp:
IgG
Proteindetails:
A-kinase anchor protein 10; mitochondrial
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody