DNAJC2 Antibody
Produktgrößen
50ul
£316,00
OACA07478-50UL
100ul
£387,00
OACA07478-100UL
Über dieses Produkt
- SKU:
- OACA07478
- Zusätzliche Namen:
- DnaJ (Hsp40) homolog; subfamily C; member 2;dnaJ homolog subfamily C member 2;M-phase phosphoprotein 11;MPHOSPH11;MPP11;ZRF1;ZUO1;zuotin-related factor 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic; acts as a molecular chaperone: component of the ribosome-associated complex (RAC); a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex; stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear; mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub); and promotes the displacement of the polycomb PRC1 complex from chromatin; thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'.
- Gendetails:
- DnaJ heat shock protein family (Hsp40) member C2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)
- Isotyp:
- IgG
- Proteindetails:
- DnaJ homolog subfamily C member 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php