AKAP8L Antibody
Produktgrößen
50ul
£316,00
OACA07466-50UL
100ul
£387,00
OACA07466-100UL
Über dieses Produkt
- SKU:
- OACA07466
- Zusätzliche Namen:
- A kinase (PRKA) anchor protein 8-like;AKAP8-like protein;A-kinase anchor protein 8-like;HA95;HAP95;Helicase A-binding protein 95;helicase A-binding protein 95 kDa;homologous to AKAP95 protein;NAKAP;NAKAP95;neighbor of AKAP95;neighbor of A-kinase anchoring protein 95;Neighbor of A-kinase-anchoring protein 95;testis tissue sperm-binding protein Li 90mP.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export (PubMed:10748171; PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA (PubMed:10761695; PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis (PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta (PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3; in this function seems to act redundantly with AKAP8 (PubMed:16980585). May be involved in regulation of pre-mRNA splicing (PubMed:17594903).
- Gendetails:
- A-kinase anchoring protein 8 like
- Host:
- Rabbit
- Immunogen:
- Recombinant Human A-kinase anchor protein 8-like protein (1-240AA)
- Isotyp:
- IgG
- Proteindetails:
- A-kinase anchor protein 8-like
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php