DKK4 Antibody
Produktgrößen
50ul
£316,00
OACA07346-50UL
100ul
£387,00
OACA07346-100UL
Über dieses Produkt
- SKU:
- OACA07346
- Zusätzliche Namen:
- dickkopf-4;dickkopf-related protein 4;DKK-4;hDkk-4.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease (By similarity).
- Gendetails:
- dickkopf WNT signaling pathway inhibitor 4
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
- Isotyp:
- IgG
- Proteindetails:
- Dickkopf-related protein 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php