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Antikörper

CD33 Antibody

Produktgrößen
50ul
£316,00
OACA07176-50UL
100ul
£387,00
OACA07176-100UL
Über dieses Produkt
SKU:
OACA07176
Zusätzliche Namen:
CD33 antigen (gp67);CD33 molecule transcript;gp67;myeloid cell surface antigen CD33;p67;sialic acid-binding Ig-like lectin 3;SIGLEC3;SIGLEC-3.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response; may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Gendetails:
CD33 molecule
Host:
Rabbit
Immunogen:
Recombinant Human Myeloid cell surface antigen CD33 protein (49-259AA)
Isotyp:
IgG
Proteindetails:
Myeloid cell surface antigen CD33
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody