CALHM1 Antibody
Produktgrößen
50ul
£316,00
OACA07172-50UL
100ul
£387,00
OACA07172-100UL
Über dieses Produkt
- SKU:
- OACA07172
- Zusätzliche Namen:
- calcium homeostasis modulator protein 1;FAM26C;family with sequence similarity 26; member C;Protein FAM26C.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Pore-forming subunit of a voltage-gated ion channel required for sensory perception of sweet; bitter and umami tastes. Specifically present in type II taste bud cells; where it plays a central role in sweet; bitter and umami taste perception by inducing ATP release from the cell; ATP acting as a neurotransmitter to activate afferent neural gustatory pathways. Acts both as a voltage-gated and calcium-activated ion channel: mediates neuronal excitability in response to changes in extracellular Ca(2+) concentration. Has poor ion selectivity and forms a wide pore (around 14 Angstroms) that mediates permeation of Ca(2+); Na(+) and K(+); as well as permeation of monovalent anions. Acts as an activator of the ERK1 and ERK2 cascade. Triggers endoplasmic reticulum stress by reducing the calcium content of the endoplasmic reticulum. May indirectly control amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
- Gendetails:
- calcium homeostasis modulator 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Calcium homeostasis modulator protein 1 protein (202-346AA)
- Isotyp:
- IgG
- Proteindetails:
- Calcium homeostasis modulator protein 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php