CISH Antibody
Produktgrößen
50ul
£316,00
OACA07135-50UL
100ul
£387,00
OACA07135-100UL
Über dieses Produkt
- SKU:
- OACA07135
- Zusätzliche Namen:
- BACTS2;CIS;CIS-1;cytokine-inducible inhibitor of signaling type 1B;cytokine-inducible SH2-containing protein;G18;Protein G18;SOCS;suppressor of cytokine signaling.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin; prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
- Gendetails:
- cytokine inducible SH2 containing protein
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cytokine-inducible SH2-containing protein (1-257AA)
- Isotyp:
- IgG
- Proteindetails:
- Cytokine-inducible SH2-containing protein
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php