ATG14 Antibody
Produktgrößen
50ul
£316,00
OACA07103-50UL
100ul
£387,00
OACA07103-100UL
Über dieses Produkt
- SKU:
- OACA07103
- Zusätzliche Namen:
- ATG14 autophagy related 14 homolog;ATG14L;autophagy-related protein 14-like protein;BARKOR;beclin 1-associated autophagy-related key regulator;Beclin 1-Interacting protein;KIAA0831.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052; PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696; PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1; but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).
- Gendetails:
- autophagy related 14
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-310AA)
- Isotyp:
- IgG
- Proteindetails:
- Beclin 1-associated autophagy-related key regulator
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php