COPS2 Antibody
Produktgrößen
50ul
£316,00
OACA06924-50UL
100ul
£387,00
OACA06924-100UL
Über dieses Produkt
- SKU:
- OACA06924
- Zusätzliche Namen:
- ALIEN;alien homolog;COP9 constitutive photomorphogenic homolog subunit 2;COP9 signalosome complex subunit 2;CSN2;JAB1-containing signalosome subunit 2;SGN2;signalosome subunit 2;thyroid receptor-interacting protein 15;TR-interacting protein 15;TRIP15;TRIP-15.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Essential component of the COP9 signalosome complex (CSN); a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes; leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF; CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53; c-jun/JUN; IkappaBalpha/NFKBIA; ITPK1 and IRF8/ICSBP; possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system; respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
- Gendetails:
- COP9 signalosome subunit 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human COP9 signalosome complex subunit 2 protein (1-310AA)
- Isotyp:
- IgG
- Proteindetails:
- COP9 signalosome complex subunit 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php