GZMA Antibody
Produktgrößen
50ul
£316,00
OACA06883-50UL
100ul
£387,00
OACA06883-100UL
Über dieses Produkt
- SKU:
- OACA06883
- Zusätzliche Namen:
- CTL tryptase;CTLA3;cytotoxic T-lymphocyte proteinase 1;Cytotoxic T-lymphocyte-associated serine esterase-3;fragmentin-1;granzyme 1;granzyme A;Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease);granzyme A (granzyme 1; cytotoxic T-lymphocyte-associated serine esterase 3);Granzyme-1;h factor;Hanukah factor serine protease);Hanukkah factor;HF;HFSP.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189'; which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
- Gendetails:
- granzyme A
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Granzyme A protein (29-262AA)
- Isotyp:
- IgG
- Proteindetails:
- Granzyme A
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php