EED Antibody
Produktgrößen
50ul
£316,00
OACA06845-50UL
100ul
£387,00
OACA06845-100UL
Über dieses Produkt
- SKU:
- OACA06845
- Zusätzliche Namen:
- COGIS;embryonic ectoderm development protein;HEED;polycomb protein EED;WAIT1;WD protein associating with integrin cytoplasmic tails 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex; which methylates 'Lys-9' and 'Lys-27' of histone H3; leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27'; whereas H3 'Lys-27' recognition has the opposite effect; enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases; thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8; HOXA9; MYT1 and CDKN2A.
- Gendetails:
- embryonic ectoderm development
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Polycomb protein EED protein (1-300AA)
- Isotyp:
- IgG
- Proteindetails:
- Polycomb protein EED
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php