CNOT8 Antibody
Produktgrößen
50ul
£316,00
OACA06830-50UL
100ul
£387,00
OACA06830-100UL
Über dieses Produkt
- SKU:
- OACA06830
- Zusätzliche Namen:
- CAF1;Caf1b;CAF1-like protein;CAF2;CALIF;CALIFp;CCR4-associated factor 8;CCR4-NOT transcription complex subunit 8;hCAF1;PGK promoter directed over production;POP2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation; miRNA-mediated repression; translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- Gendetails:
- CCR4-NOT transcription complex subunit 8
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292AA)
- Isotyp:
- IgG
- Proteindetails:
- CCR4-NOT transcription complex subunit 8
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php